@prefix ex: <https://sparql.uniprot.org/.well-known/sparql-examples/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix schema: <https://schema.org/> .
@prefix sh: <http://www.w3.org/ns/shacl#> .

ex:56 a sh:SPARQLExecutable,
        sh:SPARQLSelectExecutable ;
    rdfs:comment "Select enzymes that have ligands known to have an allosteric effect"@en ;
    rdfs:seeAlso <https://www.youtube.com/watch?v=DuSinQd9YhA> ;
    sh:prefixes _:sparql_examples_prefixes ;
    sh:select """PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX up: <http://purl.uniprot.org/core/>

SELECT
  ?protein
  ?ligandName 
  ?ligandNote
  ?chebi
WHERE {
   ?protein up:annotation ?annotation .
   ?annotation a up:Binding_Site_Annotation . 
   ?annotation up:ligand ?ligand .
   ?ligand rdfs:comment ?ligandNote ;
     rdfs:subClassOf ?chebi ;
     rdfs:label ?ligandName .
   FILTER(REGEX(?ligandNote, "allosteric", "i"))
}""" ;
    schema:keywords "enzyme" , "binding site" ;
    schema:target <https://sparql.uniprot.org/sparql/> .