@prefix ex: <https://sparql.uniprot.org/.well-known/sparql-examples/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix schema: <https://schema.org/> .
@prefix sh: <http://www.w3.org/ns/shacl#> .

ex:62_diseases_involving_enzymes a sh:SPARQLExecutable,
        sh:SPARQLSelectExecutable ;
    rdfs:comment "Find diseases that are thought to be related to enzymes"@en ;
    sh:prefixes _:sparql_examples_prefixes ;
    sh:select """PREFIX skos: <http://www.w3.org/2004/02/skos/core#>
PREFIX up: <http://purl.uniprot.org/core/>

SELECT
?disease ?diseaseLabel
WHERE {
 ?protein up:enzyme|up:annotation/up:catalyticActivity/up:enzymeClass ?enzyme ;
                   up:annotation ?diseaseAnnotation .
 ?diseaseAnnotation a up:Disease_Annotation ;
                    up:disease ?disease .
 ?disease skos:prefLabel ?diseaseLabel .
}""" ;
    schema:keywords "enzyme" , "disease" , "list" ;
    schema:target <https://sparql.uniprot.org/sparql/> .