@prefix ex: <https://sparql.uniprot.org/.well-known/sparql-examples/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix schema: <https://schema.org/> .
@prefix sh: <http://www.w3.org/ns/shacl#> .

ex:83_rhea_reactions_not_associated_with_ec_in_uniprotkb a sh:SPARQLExecutable,
        sh:SPARQLSelectExecutable ;
    rdfs:comment "List <a href=\"https://www.rhea-db.org/\">Rhea</a> reactions that are <em>not</em> associated with an <a href=\"https://iubmb.qmul.ac.uk/enzyme/index.html\">EC (enzyme classification)</a>."^^rdf:HTML ;
    sh:prefixes _:sparql_examples_prefixes ;
    sh:select """PREFIX up: <http://purl.uniprot.org/core/>

SELECT 
  ?rhea 
  ?EC 
WHERE {
  ?CatalyticActivity up:catalyzedReaction ?rhea .
  MINUS {
    ?CatalyticActivity up:enzymeClass ?EC .
  }
}""" ;
    schema:keywords "Rhea" , "enzyme classification" , "list" , "enzyme" ;
    schema:target <https://sparql.uniprot.org/sparql/> .