@prefix ex:<https://purl.expasy.org/sparql-examples/neXtProt/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix schema: <https://schema.org/> .
@prefix sh: <http://www.w3.org/ns/shacl#> .

ex:NXQ_00009 a sh:SPARQLExecutable,
        sh:SPARQLSelectExecutable ;
    rdfs:comment "Proteins with 3 disulfide bonds and that are not annotated as hormones "@en ;
    sh:prefixes _:sparql_examples_prefixes ;
    sh:select """PREFIX : <http://nextprot.org/rdf/>
PREFIX nextprot_cv: <http://nextprot.org/rdf/terminology/>

SELECT DISTINCT ?entry WHERE {
 ?entry :isoform ?isoform.
 ?isoform :ptm ?statement.
 ?statement a :DisulfideBond.
 filter not exists { ?entry :isoform / :function / :term /:childOf nextprot_cv:GO_0005179. } # GO Hormone activity
} group by ?entry ?isoform having (count(?statement) =3 )""" ;
    schema:keywords "PTM",
        "function",
        "tutorial" ;
    schema:target <https://sparql.nextprot.org/sparql> .